Effective regulation is a complex and demanding process. First an appropriate regulatory strategy needs to be developed--decisions mad about what and how to regulate. Then agencies have to be established, including the recruitment of staff and the collection of data. Then the detailed rules have to be written. Next they have to be applied to specific cases. Monitoring processes need to be established so that violators can be identified and either persuaded to change their behavior or penalized if they do not. All of this must be done in a context in which those being regulated will protest and seek to influence the agency to treat them more leniently. Effective regulation thus requires a demanding combination of technical expertise, administrative capacity, and political support that is not always easy for nations to provide.
From Roberts and Hsiao. From certain vantage points, it's a wonder that any countries or states have high-functioning, well-respected regulatory systems. And certainly not a surprise that poorly financed governments have such trouble enacting effective regulatory systems.